Balancing selection in self?fertilizing populations

Self?fertilization commonly occurs in hermaphroditic species, either occasionally or as the main reproductive mode. It strongly affects genetic functioning of a population by increasing homozygosity and drift reducing effectiveness recombination. Balancing selection is form that maintains polymorphism, which has been extensively studied outcrossing species. Yet, despite recent developments, analysis balancing partially selfing species limited to specific cases general treatment still lacking. In particular, it unclear whether globally reduced efficacy well?known case overdominance. I provide unifying framework, quantify how maintenance polymorphism different selection, show they can be classified into two categories: overdominance?like (including true overdominance, variable space time, antagonistic selection), affected selfing, negative frequency dependent barely even at multiple loci. also simple analytical results for all under assumption weak selection. This framework provides theoretical background analyze genomic signature sheds new light on evolution including syndrome, interaction with pathogens, evolutionary fate lineages.